Rhizobiales-Specific RirA Represses a Naturally “Synthetic” Foreign Siderophore Gene Cluster To Maintain Sinorhizobium-Legume Mutualism

ABSTRACT Iron homeostasis is strictly regulated in cellular organisms. The Rhizobiales order enriched with symbiotic and pathogenic bacteria has evolved a lineage-specific regulator, RirA, responding to iron fluctuations. However, the regulatory role of RirA in bacterium-host interactions remains la...

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Bibliographic Details
Main Authors: Ke-Han Liu, Biliang Zhang, Bo-Sen Yang, Wen-Tao Shi, Yu-Fei Li, Yin Wang, Pan Zhang, Jian Jiao, Chang-Fu Tian
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02900-21