Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study

Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study

Neuroblastoma (NB) is the most common extra-cranial malignancy in preschool children. To portray the genetic landscape of an overly aggressive NB leading to a rapid clinical progression of the disease, tumor DNA collected pre- and post-treatment has been analyzed. Array comparative genomic hybridiza...

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Bibliographic Details
Main Authors: Diana Corallo, Carlo Zanon, Marcella Pantile, Gian Paolo Tonini, Angelica Zin, Samuela Francescato, Bartolomeo Rossi, Eva Trevisson, Claudia Pinato, Ezequiel Monferrer, Rosa Noguera, Salvador F. Aliño, Maria Jose Herrero, Alessandra Biffi, Elisabetta Viscardi, Sanja Aveic
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Neuroblastoma
recurrent tumor
array CGH
clonal evolution
whole exome sequencing
3D tumoroids
Online Access:https://www.mdpi.com/2073-4409/10/10/2695

Internet

https://www.mdpi.com/2073-4409/10/10/2695

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