Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17

Abstract Blue light is part of the natural light spectrum that emits high energy. Currently, people are frequently exposed to blue light from 3C devices, resulting in a growing incidence of retinopathy. The retinal vasculature is complex, and retinal vessels not only serve the metabolic needs of the...

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Bibliographic Details
Main Authors: Yen-Ju Chan, George Hsiao, Wang-Nok Wan, Tsung-Min Yang, Chi-Hao Tsai, Jaw-Jou Kang, Yu-Cheng Lee, Te-Chao Fang, Yu-Wen Cheng, Ching-Hao Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-023-00430-7