Leading edge maintenance in migrating cells is an emergent property of branched actin network growth

Animal cell migration is predominantly driven by the coordinated, yet stochastic, polymerization of thousands of nanometer-scale actin filaments across micron-scale cell leading edges. It remains unclear how such inherently noisy processes generate robust cellular behavior. We employed high-speed im...

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Bibliographic Details
Main Authors: Rikki M Garner, Julie A Theriot
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/74389