Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery

Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery

This study aimed to develop a chemically stable niosomal eye drop containing fosinopril (FOS) for lowering intraocular pressure. The effects of cyclodextrin (CD), surfactant types and membrane stabilizer/charged inducers on physiochemical and chemical properties of niosome were evaluated. The pH val...

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Bibliographic Details
Main Authors: Hay Marn Hnin, Einar Stefánsson, Thorsteinn Loftsson, Rathapon Asasutjarit, Dusadee Charnvanich, Phatsawee Jansook
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
cyclodextrin
ophthalmic
fosinopril sodium
niosomes
encapsulation
stabilization
Online Access:https://www.mdpi.com/1999-4923/14/6/1147

Internet

https://www.mdpi.com/1999-4923/14/6/1147

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