Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise

Pathological endoplasmic reticulum (ER) stress is tightly linked to the accumulation of reactive oxidants, which can be both upstream and downstream of ER stress. Accordingly, detrimental intracellular stress signals are amplified through establishment of a vicious cycle. An increasing number of hum...

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Bibliographic Details
Main Authors: Julia eBirk, Thomas eRamming, Alex eOdermatt, Christian eAppenzeller-Herzog
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00108/full