Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling

Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling

Taxifolin (TA) is a natural flavonoid found in many foods and medicinal plants with well-documented antioxidant and anti-inflammatory properties. Cyclophosphamide (CP) is an effective antineoplastic and immunosuppressive agent; however, it is associated with numerous adverse events, including hepat...

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Bibliographic Details
Main Authors: Osama Y. Althunibat, Mohammad H. Abukhalil, Muthana M. Jghef, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Bader Alsuwayt, Reem Alazragi, Mohammed A. S. Abourehab, Afaf F. Almuqati, Shaik Karimulla, Saleem H. Aladaileh
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-07-01
Series:Biomolecules & Biomedicine
Subjects:
Flavonoids
cyclophosphamide
inflammation
taxifolin
hepatotoxicity
oxidative damage
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/8743

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/8743

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