Comparing morphology, flow cytometry and molecular genetics in the assessment of minimal residual disease in children with B-acute lymphoblastic leukaemia (B-ALL)

Comparing morphology, flow cytometry and molecular genetics in the assessment of minimal residual disease in children with B-acute lymphoblastic leukaemia (B-ALL)

ackground:Minimal residual disease (MRD) detection has been shown to be the best prognostic factor in B-acute lymphoblastic leukaemia (B-ALL). Multicolour flow cytometry (FCM) and specific molecular aberrations (MOL) are the classic techniques used to assess MRD. The former is faster and less costly...

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Bibliographic Details
Main Authors: Candice L. Hendricks, Suvarna Buldeo, Dashini Pillay, Ashendran Naidoo, Rajendra Thejpal, Nadine Rapiti, Beverley Neethling, Yasmin Goga, Hamida van Staaden
Format: Article
Language:English
Published: AOSIS 2019-10-01
Series:South African Journal of Oncology
Subjects:
minimal residual disease
b-acute lymphoblastic leukaemia
paediatric
flow cytometry
molecular genetics
Online Access:https://sajo.org.za/index.php/sajo/article/view/76

Internet

https://sajo.org.za/index.php/sajo/article/view/76

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