Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation

Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation

Glycine receptor (GlyR) autoantibodies are associated with stiff-person syndrome and the life-threatening progressive encephalomyelitis with rigidity and myoclonus in children and adults. Patient histories show variability in symptoms and responses to therapeutic treatments. A better understanding o...

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Bibliographic Details
Main Authors: Vera Rauschenberger, Inken Piro, Vikram Babu Kasaragod, Verena Hörlin, Anna-Lena Eckes, Christoph J. Kluck, Hermann Schindelin, Hans-Michael Meinck, Jonathan Wickel, Christian Geis, Erdem Tüzün, Kathrin Doppler, Claudia Sommer, Carmen Villmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
glycine receptor
autoantibodies
glycosylation
extracellular domain
adsorption
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1089101/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1089101/full

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