Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme

The use of bifunctional catalysts in organic synthesis finds inspiration in the selectivity of enzymatic catalysis which arises from the specific interactions between basic and acidic amino acid residues and the substrate itself in order to stabilize developing charges in the transition state. Many...

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Bibliographic Details
Main Authors: Alberto Macone, Alberto Boffi, Bruno Botta, Marco Barba, Alessandra Bonamore
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/4/2070/