Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme
The use of bifunctional catalysts in organic synthesis finds inspiration in the selectivity of enzymatic catalysis which arises from the specific interactions between basic and acidic amino acid residues and the substrate itself in order to stabilize developing charges in the transition state. Many...
Main Authors: | Alberto Macone, Alberto Boffi, Bruno Botta, Marco Barba, Alessandra Bonamore |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-03-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/15/4/2070/ |
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