Sea urchin (Diadema savignyi) extract as a novel protective agent against cisplatin induced neurotoxicity in rats

Abstract Neurotoxicity is a severe side effect of platinum compounds used for cancer chemotherapy such as Cisplatin. This neurotoxicity leads to severe cognitive and nervous dysfunction, therefore, limiting the dose of Cisplatin and compromising the treatment protocol. The present study investigates...

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Bibliographic Details
Main Authors: Eman A. Khalil, Hamdy Swelim, Hala El-Tantawi, Ahmed Abdellatif
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-023-00651-4