Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose

The adenosine A2B receptor (A2BAR) is a member of a family of G-protein coupled receptors (GPCRs), which has a low affinity for adenosine and is now implicated in several pathophysiological conditions. We have demonstrated the beneficial effects of A2BAR activation in enhancing recovery after acute...

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Bibliographic Details
Main Authors: Giselle Sanchez-Guerrero, David S. Umbaugh, Abhay A. Ramachandran, Antonio Artigues, Hartmut Jaeschke, Anup Ramachandran
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Livers
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Online Access:https://www.mdpi.com/2673-4389/4/1/2