Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents

Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents

Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering natural plant-derived products seems to be a promising strategy. The phytochemical Rocaglamide A (Roc-A) and its derivatives rise as an inter...

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Bibliographic Details
Main Authors: Igor V.F. dos Santos, Rosivaldo S. Borges, Guilherme M. Silva, Lúcio R. de Lima, Ruan S. Bastos, Ryan S. Ramos, Luciane B. Silva, Carlos H. T. P. da Silva, Cleydson B. R. dos Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
hierarchical virtual screening
rocaglamide
skin cancer
anticancer activity
pharmacophore
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.836572/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.836572/full

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