Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

<p>Abstract</p> <p>Background</p> <p>Metastasis is a multi-step process that is responsible for the majority of deaths in cancer patients. Current treatments are not effective in targeting metastasis. The molecular chaperone hsp90α is secreted from invasive cancer cells...

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Bibliographic Details
Main Authors: Chan Doug, Sims Jessica D, McCready Jessica, Jay Daniel G
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/294