Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis

Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis

Tuberculosis (TB), caused by <i>Mycobacterium tuberculosis</i> (Mtb), remains a leading cause of pediatric morbidity and mortality. Young children are at high risk of TB following Mtb exposure, and this vulnerability is secondary to insufficient host immunity during early life. Our prima...

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Bibliographic Details
Main Authors: Erin Morrow, Qijia Liu, Sarah Kiguli, Gwendolyn Swarbrick, Mary Nsereko, Megan D. Null, Meghan Cansler, Harriet Mayanja-Kizza, W. Henry Boom, Phalkun Chheng, Melissa R. Nyendak, David M. Lewinsohn, Deborah A. Lewinsohn, Christina L. Lancioni
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pathogens
Subjects:
pediatric
<i>Mycobacterium tuberculosis</i>
adaptive immunity
cytokines
T cells
Online Access:https://www.mdpi.com/2076-0817/12/11/1353

Internet

https://www.mdpi.com/2076-0817/12/11/1353

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