Self-organized Kidney Rudiments: Prospects for Better Nephrotoxicity Assays
Kidneys are essential to life but vulnerable to a range of toxicants, including therapeutic drugs and their metabolites. Indeed, nephrotoxicity is often a limiting factor in both drug use and drug development. Most toxicants damage kidneys by one of four mechanisms: damage to the membrane and its ju...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2015-01-01
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| Series: | Biomarker Insights |
| Online Access: | https://doi.org/10.4137/BMI.S20056 |