Time-Course Transcriptome Analysis of Lungs From Mice Infected With Hypervirulent Klebsiella pneumoniae via Aerosolized Intratracheal Inoculation

Time-Course Transcriptome Analysis of Lungs From Mice Infected With Hypervirulent Klebsiella pneumoniae via Aerosolized Intratracheal Inoculation

Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening community-acquired infections among healthy young individuals and is thus of concern for global dissemination. In this study, a mouse model of acute primary hvKp pneumonia was established via aerosolized intratracheal (i.t.) inocu...

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Bibliographic Details
Main Authors: Xinying Zheng, Jianshu Guo, Chaoyue Cao, Tongtong Qin, Yue Zhao, Xiaolin Song, Meng Lv, Lingfei Hu, Lili Zhang, Dongsheng Zhou, Tongyu Fang, Wenhui Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
hypervirulent Klebsiella pneumoniae
molecular pathology
lung
time-course transcriptome
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.833080/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.833080/full

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