T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display

T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display

The HIV-1 mature capsid (CA) assumes an amorphous, fullerene conical configuration due to its high flexibility. How native CA self-assembles is still unclear despite having well-defined structures of its pentamer and hexamer building blocks. Here we explored the self-assembly of an engineered capsid...

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Bibliographic Details
Main Authors: Zhiqing Zhang, Maozhou He, Shimeng Bai, Feng Zhang, Jie Jiang, Qingbing Zheng, Shuangquan Gao, Xiaodong Yan, Shaowei Li, Ying Gu, Ningshao Xia
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Viruses
Subjects:
HIV-1 capsid
T = 4 icosahedral
assembly
cryo electron microscopy
epitope display
Online Access:https://www.mdpi.com/1999-4915/10/12/667

Internet

https://www.mdpi.com/1999-4915/10/12/667

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