Formaldehyde analysis of seized cosmetic products by HS-GC-MS of methylal, ethoxymethoxymethane, and ethylal derivatives

Abstract Formaldehyde is a carcinogenic compound used as preservative in cosmetic products. In this study, a derivatization procedure using MeOH, EtOH and HCl (25:25:1), and incubation at 60ºC for 4 hours was optimized, and the derivatized products - methylal, ethoxymethoxymethane (EMM), and ethylal...

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Bibliographic Details
Main Authors: Ettore Ferrari Júnior, Lívia Barros Salum, Robiedson Romeiro Damasceno, Bárbara Elisa Pereira Alves, Eloisa Dutra Caldas
Format: Article
Language:English
Published: Universidade de São Paulo 2022-11-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100737&lng=en&tlng=en