Generation of Leydig-like cells: approaches, characterization, and challenges

Generation of Leydig-like cells: approaches, characterization, and challenges

Testosterone production by Leydig cells (LCs) plays a crucial role in male reproduction. The functional degeneration of LCs can cause testosterone deficiency, ultimately resulting in primary male hypogonadism. Transplantation of exogenous LCs with the ability to produce testosterone in response to t...

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Bibliographic Details
Main Authors: Zhao-Hui Li, Jun-Dong Lu, Shi-Jun Li, Hao-Lin Chen, Zhi-Jian Su
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Journal of Andrology
Subjects:
fibroblasts; hypogonadism; leydig-like cells; reprogramming; stem cells
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=4;spage=335;epage=344;aulast=Li

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=4;spage=335;epage=344;aulast=Li

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