Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation.

BACKGROUND: Chondroitin sulfate proteoglycan (CSPG) is a major component of the glial scar. It is considered to be a major obstacle for central nervous system (CNS) recovery after injury, especially in light of its well-known activity in limiting axonal growth. Therefore, its degradation has become...

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Bibliographic Details
Main Authors: Asya Rolls, Ravid Shechter, Anat London, Yifat Segev, Jasmin Jacob-Hirsch, Ninette Amariglio, Gidon Rechavi, Michal Schwartz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2517615?pdf=render