Axonal injury in asymptomatic individuals preceding onset of multiple sclerosis

Abstract Axonal loss is the main cause of irreversible disability in multiple sclerosis (MS). Serum neurofilament light (sNfL) is a biomarker of axonal disintegration. In this nested case–control study, blood samples from 519 presymptomatic persons (age range 4–39 years) who later received an MS dia...

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Bibliographic Details
Main Authors: Daniel Jons, Henrik Zetterberg, Martin Biström, Lucia Alonso‐Magdalena, Martin Gunnarsson, Magnus Vrethem, Kaj Blennow, Staffan Nilsson, Peter Sundström, Oluf Andersen
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51568