Biomarkers of Immunotherapy Response in Patients with Non-Small-Cell Lung Cancer: Microbiota Composition, Short-Chain Fatty Acids, and Intestinal Permeability

Biomarkers of Immunotherapy Response in Patients with Non-Small-Cell Lung Cancer: Microbiota Composition, Short-Chain Fatty Acids, and Intestinal Permeability

Immune checkpoint inhibitors have been proposed as the standard treatment for different stages of non-small-cell lung cancer in multiple indications. Not all patients benefit from these treatments, however, and certain patients develop immune-related adverse events. Although the search for predictor...

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Bibliographic Details
Main Authors: Alba Moratiel-Pellitero, María Zapata-García, Marta Gascón-Ruiz, Andrea Sesma, Elisa Quílez, Ariel Ramirez-Labrada, Luis Martínez-Lostao, María Pilar Domingo, Patricia Esteban, Alfonso Yubero, Raquel Barbero-Herranz, Ana Moreno-Blanco, José Ramón Paño, Rodrigo Lastra, Julián Pardo, Dolores Isla, Rosa del Campo, Eva Gálvez
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
NSCLC
predictive biomarkers
ICI response
irAEs
gut microbiota
intestinal permeability
Online Access:https://www.mdpi.com/2072-6694/16/6/1144

Internet

https://www.mdpi.com/2072-6694/16/6/1144

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