Binding of Alpha-Crystallin to Cortical and Nuclear Lens Lipid Membranes Derived from a Single Lens

Binding of Alpha-Crystallin to Cortical and Nuclear Lens Lipid Membranes Derived from a Single Lens

Several studies reported that α-crystallin concentrations in the eye lens cytoplasm decrease with a corresponding increase in membrane-bound α-crystallin with age and cataracts. The influence of the lipid and cholesterol composition difference between cortical membrane (CM) and nuclear membrane (NM)...

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Bibliographic Details
Main Authors: Raju Timsina, Samantha Wellisch, Dieter Haemmerle, Laxman Mainali
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
α-crystallin
single lens
cortical membrane (CM)
nuclear membrane (NM)
percentage of membrane surface occupied (MSO)
binding affinity (K<sub>a</sub>)
Online Access:https://www.mdpi.com/1422-0067/23/19/11295

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https://www.mdpi.com/1422-0067/23/19/11295

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