Dengue virus-like particles mimic the antigenic properties of the infectious dengue virus envelope

Abstract Background The 4 dengue serotypes (DENV) are mosquito-borne pathogens that are associated with severe hemorrhagic disease. DENV particles have a lipid bilayer envelope that anchors two membrane glycoproteins prM and E. Two E-protein monomers form head-to-tail homodimers and three E-dimers a...

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Bibliographic Details
Main Authors: Stefan W. Metz, Ashlie Thomas, Laura White, Mark Stoops, Markus Corten, Holger Hannemann, Aravinda M. de Silva
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Virology Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12985-018-0970-2