An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii.

Cryptococcosis is a potentially lethal fungal infection of humans caused by organisms within the Cryptococcus neoformans/gattii species complex. Whilst C. neoformans is a relatively common pathogen of immunocompromised individuals, C. gattii is capable of acting as a primary pathogen of immunocompet...

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Bibliographic Details
Main Authors: Lamin Saidykhan, Joao Correia, Andrey Romanyuk, Anna F A Peacock, Guillaume E Desanti, Leanne Taylor-Smith, Maria Makarova, Elizabeth R Ballou, Robin C May
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010321