REGA-SIGN: Development of a Novel Set of NanoBRET-Based G Protein Biosensors

REGA-SIGN: Development of a Novel Set of NanoBRET-Based G Protein Biosensors

Despite G protein-coupled receptors (GPCRs) being important theapeutic targets, the signaling properties of many GPCRs remain poorly characterized. GPCR activation primarily initiates heterotrimeric G protein signaling. To detect ligand-induced G protein activation, Bioluminescence Resonance Energy...

Full description

Bibliographic Details
Main Authors: Katrijn Boon, Nathan Vanalken, Eef Meyen, Dominique Schols, Tom Van Loy
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biosensors
Subjects:
NanoBRET
G protein activation
G protein-coupled receptor
biosensor
kinetic
Online Access:https://www.mdpi.com/2079-6374/13/8/767

Similar Items

Similar Items