ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling

ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling

We investigated the functional role of ATF2, a transcription factor normally activated via its phosphorylation in response to phospho-ERK/MAPK signals, in the outgrowth of urothelial cancer. In both neoplastic and non-neoplastic urothelial cells, the expression levels of androgen receptor (AR) corre...

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Bibliographic Details
Main Authors: Satoshi Inoue, Taichi Mizushima, Hiroki Ide, Guiyang Jiang, Takuro Goto, Yujiro Nagata, George J Netto, Hiroshi Miyamoto
Format: Article
Language:English
Published: Bioscientifica 2018-11-01
Series:Endocrine Connections
Subjects:
androgen receptor
ATF2
ERK
neoplastic transformation
prognosticator
tumor progression
urothelial cancer
Online Access:https://ec.bioscientifica.com/view/journals/ec/7/12/EC-18-0364.xml

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https://ec.bioscientifica.com/view/journals/ec/7/12/EC-18-0364.xml

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