Downregulation of GDF15 suppresses ferroptosis and predicts unfavorable prognosis in clear cell renal cell carcinoma

Downregulation of GDF15 suppresses ferroptosis and predicts unfavorable prognosis in clear cell renal cell carcinoma

Abstract Background Growth differentiation factor 15 (GDF15), a member of the transforming growth factor beta (TGF-β) superfamily, is involved in various pathophysiological processes such as anorexia, obesity, inflammation, and tumorigenesis. However, the role of GDF15 in clear cell renal cell carci...

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Bibliographic Details
Main Authors: Dongliang Yang, Zhongyin He, Jiawei Lu, Xiaolin Yuan, Haiyong Liu, Yagang Xue, Ting Chen, Hongxing Gu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cell Division
Subjects:
ccRCC
GDF15
Ferroptosis
TCGA-KIRC
Biomarker
Online Access:https://doi.org/10.1186/s13008-023-00103-9

Internet

https://doi.org/10.1186/s13008-023-00103-9

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