Early Effects of Extracellular Vesicles Secreted by Adipose Tissue Mesenchymal Cells in Renal Ischemia Followed by Reperfusion: Mechanisms Rely on a Decrease in Mitochondrial Anion Superoxide Production

Early Effects of Extracellular Vesicles Secreted by Adipose Tissue Mesenchymal Cells in Renal Ischemia Followed by Reperfusion: Mechanisms Rely on a Decrease in Mitochondrial Anion Superoxide Production

Acute kidney injury (AKI) caused by ischemia followed by reperfusion (I/R) is characterized by intense anion superoxide (O<sub>2</sub><sup>•−</sup>) production and oxidative damage. We investigated whether extracellular vesicles secreted by adipose tissue mesenchymal cells (E...

Full description

Bibliographic Details
Main Authors: Jarlene A. Lopes, Federica Collino, Clara Rodrigues-Ferreira, Luzia da Silva Sampaio, Glória Costa-Sarmento, Camila H. C. Wendt, Fernando P. Almeida, Kildare R. Miranda, Tais H. Kasai-Brunswick, Rafael S. Lindoso, Adalberto Vieyra
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
mesenchymal cells
proximal tubular cells
renal ischemia/reperfusion
mitochondria
anion superoxide
Online Access:https://www.mdpi.com/1422-0067/23/6/2906

Internet

https://www.mdpi.com/1422-0067/23/6/2906

Similar Items