Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma

Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma

Background: The prognosis of adrenocortical carcinoma (ACC) is heterogeneous. Genomic studies have identified ACC subgroups characterized by specific m olecular alterations, including features measured at DNA level (somatic mutations, chromosome alterations, DNA methylation), which are closely assoc...

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Main Authors: Anne Jouinot, Juliane Lippert, Martin Fassnacht, Bruno de La Villeon, Amandine Septier, Mario Neou, Karine Perlemoine, Silke Appenzeller, Mathilde Sibony, Sébastien Gaujoux, Bertrand Dousset, Rossella Libe, Lionel Groussin, Cristina L Ronchi, Guillaume Assié, Jérôme Bertherat
Format: Article
Language:English
Published: Bioscientifica 2020-08-01
Series:Endocrine Connections
Subjects:
adrenocortical carcinoma
intratumor heterogeneity
methylation
chromosome alterations
somatic mutations
Online Access:https://ec.bioscientifica.com/view/journals/ec/9/7/EC-20-0228.xml

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https://ec.bioscientifica.com/view/journals/ec/9/7/EC-20-0228.xml

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