The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers

The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers

ABSTRACT Whole-genome sequence (WGS) data are commonly used to design diagnostic targets for the identification of bacterial pathogens. To do this effectively, genomics databases must be comprehensive to identify the strict core genome that is specific to the target pathogen. As additional genomes a...

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Bibliographic Details
Main Authors: Jason W. Sahl, Adam J. Vazquez, Carina M. Hall, Joseph D. Busch, Apichai Tuanyok, Mark Mayo, James M. Schupp, Madeline Lummis, Talima Pearson, Kenzie Shippy, Rebecca E. Colman, Christopher J. Allender, Vanessa Theobald, Derek S. Sarovich, Erin P. Price, Alex Hutcheson, Jonas Korlach, John J. LiPuma, Jason Ladner, Sean Lovett, Galina Koroleva, Gustavo Palacios, Direk Limmathurotsakul, Vanaporn Wuthiekanun, Gumphol Wongsuwan, Bart J. Currie, Paul Keim, David M. Wagner
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00846-16

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https://journals.asm.org/doi/10.1128/mBio.00846-16

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