p16 Expression Differentiates High-Risk Gastrointestinal Stromal Tumor and Predicts Poor Outcome

Gastrointestinal stromal tumors (GISTs) are characterized by alterations in genes involved in cell cycle regulation. Although p16 (INK4A) have been extensively investigated in GISTs, there are still discrepancies regarding its prognostic value. Therefore, we evaluated the clinical occurrence, diagno...

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Bibliographic Details
Main Authors: Michael Schmieder, Sebastian Wolf, Bettina Danner, Susanne Stoehr, Markus S. Juchems, Peter Wuerl, Doris Henne-Bruns, Uwe Knippschild, Cornelia Hasel, Klaus Kramer
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801066