p16 Expression Differentiates High-Risk Gastrointestinal Stromal Tumor and Predicts Poor Outcome
Gastrointestinal stromal tumors (GISTs) are characterized by alterations in genes involved in cell cycle regulation. Although p16 (INK4A) have been extensively investigated in GISTs, there are still discrepancies regarding its prognostic value. Therefore, we evaluated the clinical occurrence, diagno...
Main Authors: | Michael Schmieder, Sebastian Wolf, Bettina Danner, Susanne Stoehr, Markus S. Juchems, Peter Wuerl, Doris Henne-Bruns, Uwe Knippschild, Cornelia Hasel, Klaus Kramer |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-10-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558608801066 |
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