Examining the potential causal relationships among smoking behaviors, blood DNA methylation profiles, and the development of coronary heart disease and myocardial infarction

Examining the potential causal relationships among smoking behaviors, blood DNA methylation profiles, and the development of coronary heart disease and myocardial infarction

Abstract Background Smoking has been identified as a standalone risk factor for coronary heart disease (CHD) and myocardial infarction (MI), but the precise underlying mechanisms remain incompletely elucidated. Results In this study, we conducted a two-sample Mendelian randomization analysis to exam...

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Bibliographic Details
Main Authors: Wenhua Li, Pan Dong, Yixiao Li, Jiaxin Tang, Siyang Liu, Ling Tu, Xizhen Xu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Clinical Epigenetics
Subjects:
Smoking
Smoking-related methylation
Coronary heart disease
Myocardial infarction
Online Access:https://doi.org/10.1186/s13148-024-01791-y

Internet

https://doi.org/10.1186/s13148-024-01791-y

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