<i>Coptidis Rhizoma</i> Extract Reverses 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells via Modulation of Thymidylate Synthase

<i>Coptidis Rhizoma</i> Extract Reverses 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells via Modulation of Thymidylate Synthase

Colorectal cancer (CRC) is a malignancy of the colon or rectum. It is ranked as the third most common cancer in both men and women worldwide. Early resection permitted by early detection is the best treatment, and chemotherapy is another main treatment, particularly for patients with advanced CRC. A...

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Bibliographic Details
Main Authors: Yong-Hwi Kang, Jin-Seok Lee, Nam-Hun Lee, Seung-Hyung Kim, Chang-Seob Seo, Chang-Gue Son
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
colorectal cancer
chemoresistance
5-fluorouracil
thymidylate synthase
<i>Coptidis rhizoma</i>
Online Access:https://www.mdpi.com/1420-3049/26/7/1856

Internet

https://www.mdpi.com/1420-3049/26/7/1856

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