Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction.

Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction.

The extracellular matrix plays an important role in tissue regeneration. We investigated whether extracellular matrix protein fragments could be targeted with antibodies to ischemically injured myocardium to promote angiogenesis and myocardial repair.Four peptides, 2 derived from fibronectin and 2 d...

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Bibliographic Details
Main Authors: Shirley S Mihardja, Dongwei Gao, Richard E Sievers, Qizhi Fang, Jinjin Feng, Jianming Wang, Henry F Vanbrocklin, James W Larrick, Manley Huang, Michael Dae, Randall J Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2860995?pdf=render

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http://europepmc.org/articles/PMC2860995?pdf=render

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