The Prognostic and Predictive Role of Xeroderma Pigmentosum Gene Expression in Melanoma

The Prognostic and Predictive Role of Xeroderma Pigmentosum Gene Expression in Melanoma

BackgroundAssessment of immune-specific markers is a well-established approach for predicting the response to immune checkpoint inhibitors (ICIs). Promising candidates as ICI predictive biomarkers are the DNA damage response pathway genes. One of those pathways, which are mainly responsible for the...

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Bibliographic Details
Main Authors: Sarah Fischer, Mohamed Hamed, Steffen Emmert, Olaf Wolkenhauer, Georg Fuellen, Alexander Thiem
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
melanoma
anti-PD-1
biomarker
DNA damage response
nucleotide excision repair
xeroderma pigmentosum
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.810058/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.810058/full

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