Characterization of Host and Microbial Determinants in Individuals with Latent Tuberculosis Infection Using a Human Granuloma Model

ABSTRACT Granulomas sit at the center of tuberculosis (TB) immunopathogenesis. Progress in biomarkers and treatment specific to the human granuloma environment is hindered by the lack of a relevant and tractable infection model that better accounts for the complexity of the host immune response as w...

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Bibliographic Details
Main Authors: Evelyn Guirado, Uchenna Mbawuike, Tracy L. Keiser, Jesus Arcos, Abul K. Azad, Shu-Hua Wang, Larry S. Schlesinger
Format: Article
Language:English
Published: American Society for Microbiology 2015-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02537-14