Heart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathy.

Heart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathy.

Dilated cardiomyopathy (DCM) is a public health problem with no available curative treatment, and mitochondrial dysfunction plays a critical role in its development. The present study is the first to analyze the mitochondrial proteome in cardiac tissue of patients with DCM to identify potential mole...

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Bibliographic Details
Main Authors: Esther Roselló-Lletí, Estefanía Tarazón, María G Barderas, Ana Ortega, Manuel Otero, Maria Micaela Molina-Navarro, Francisca Lago, Jose Ramón González-Juanatey, Antonio Salvador, Manuel Portolés, Miguel Rivera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232587?pdf=render

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http://europepmc.org/articles/PMC4232587?pdf=render

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