B7 Family Molecule VSIG4 Regulates Intestinal Anti-<i>Enterohemorrhagic Escherichia coli</i> Immunity by Altering Gut Flora Diversity

B7 Family Molecule VSIG4 Regulates Intestinal Anti-<i>Enterohemorrhagic Escherichia coli</i> Immunity by Altering Gut Flora Diversity

As an essential member of the B7 family, V-set and immunoglobulin domain-containing 4 (VSIG4) is expressed explicitly in tissue-resident macrophages (TRMs) and plays an essential role in maintaining the homeostasis of the environmental immune system. Here, we demonstrate that gene-targeted VSIG4-def...

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Bibliographic Details
Main Authors: Zhili He, Jiajia Li, Saisai Gong, Li Xing, Yakun Sun, Jianxin Wang, Tao Li, Nianzhi Ning, Liangyan Zhang, Wenjing Yu, Deyan Luo, Hui Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Microorganisms
Subjects:
VSIG4
B7
EHEC
intestinal microorganism
intestinal immunity
Online Access:https://www.mdpi.com/2076-2607/9/8/1769

Internet

https://www.mdpi.com/2076-2607/9/8/1769

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