Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents

Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents

Herpes simplex virus type 1 (HSV-1) is an extremely widespread pathogen characterized by recurrent infections. HSV-1 most commonly causes painful blisters or sores around the mouth or on the genitals, but it can also cause keratitis or, rarely, encephalitis. First-line and second-line antiviral drug...

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Bibliographic Details
Main Authors: Victor P. Krasnov, Valeriya L. Andronova, Alexander V. Belyavsky, Sophia S. Borisevich, George A. Galegov, Oleg F. Kandarakov, Dmitry A. Gruzdev, Olga A. Vozdvizhenskaya, Galina L. Levit
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
herpes simplex virus
in vitro antiviral activity
drug resistance
high-throughput sequencing
mutation analysis
molecular docking
Online Access:https://www.mdpi.com/1420-3049/28/21/7375

Internet

https://www.mdpi.com/1420-3049/28/21/7375

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