Fast multiple-trait genome-wide association analysis for correlated longitudinal measurements

Abstract Large-scale longitudinal biobank data can be leveraged to identify genetic variation contributing to human diseases progression and traits trajectories. While methods for genome-wide association studies (GWAS) of multiple correlated traits have been proposed, an efficient multiple-trait app...

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Bibliographic Details
Main Authors: Gamal Abdel-Azim, Parth Patel, Shuwei Li, Shicheng Guo, Mary Helen Black
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47555-1