Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock

Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock

ABSTRACT Sepsis caused by Gram-negative bacteria is the consequence of an unrestrained infection that continuously releases lipopolysaccharide (LPS) into the bloodstream, which triggers an uncontrolled systemic inflammatory response leading to multiorgan failure and death. After scrutinizing the imm...

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Bibliographic Details
Main Authors: Marcos J. Ramos-Benitez, Caleb Ruiz-Jimenez, Jose J. Rosado-Franco, Willy D. Ramos-Pérez, Loyda B. Mendez, Antonio Osuna, Ana M. Espino
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mSphere
Subjects:
CD38
Fasciola hepatica
cytokines
fatty acid binding protein
macrophages
septic shock
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00548-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00548-18

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