Targeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells

Targeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells

Abstract Regulatory T cells (Tregs) are a key determinant for the immunosuppressive and premetastatic niche for cancer progression after surgery resection. However, the precise mechanisms regulating Tregs function during surgical stress-facilitated cancer metastasis remain unknown. This study aims t...

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Bibliographic Details
Main Authors: Yi Jiang, Shenjia Gao, Hao Sun, Xinyi Wu, Jiahui Gu, Han Wu, Yun Liao, Ronen Ben-Ami, Changhong Miao, Rong Shen, Jinlong Liu, Wankun Chen
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06396-6

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https://doi.org/10.1038/s41419-023-06396-6

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