Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass

Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass

IntroductionNobiletin is a polymethoxyflavonoid abundant in citrus peels and has been reported to have various bioactive effects. We have previously reported that nobiletin inhibits endoplasmic reticulum stress-induced apoptosis in the pancreatic β-cell line INS-1 and that continuous subcutaneous ad...

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Bibliographic Details
Main Authors: Megumi Kaji, Yukiko K. Kaneko, Stella Amarachi Ihim, Ran Kanoh, Moe Yamamoto, Momoka Yamaguchi, Tomohisa Ishikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Nutrition
Subjects:
Shiikuwasha extract
nobiletin
type 2 diabetes
db/db mice
pancreatic β-cells
insulin
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1336133/full

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https://www.frontiersin.org/articles/10.3389/fnut.2023.1336133/full

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