Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance

Objective: Nicotinamide phosphoribosyl transferase (NAMPT) is the rate-limiting enzyme in the salvage pathway that produces nicotinamide adenine dinucleotide (NAD+), an essential co-substrate regulating a myriad of signaling pathways. We produced a mouse that overexpressed NAMPT in skeletal muscle (...

Повний опис

Бібліографічні деталі
Автори: Sheila R. Costford, Bram Brouwers, Meghan E. Hopf, Lauren M. Sparks, Mauro Dispagna, Ana P. Gomes, Heather H. Cornnell, Chris Petucci, Peter Phelan, Hui Xie, Fanchao Yi, Glenn A. Walter, Timothy F. Osborne, David A. Sinclair, Randall L. Mynatt, Julio E. Ayala, Stephen J. Gardell, Steven R. Smith
Формат: Стаття
Мова:English
Опубліковано: Elsevier 2018-01-01
Серія:Molecular Metabolism
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S2212877817306816

Інтернет

http://www.sciencedirect.com/science/article/pii/S2212877817306816

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