Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HBV Replication through Production of IFN-γ and TNF-⍺

Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HBV Replication through Production of IFN-γ and TNF-⍺

Summary: The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress hepatitis B virus (HBV) infection. After adoptive transfer, PSC-CTLs can infiltrate into the liver to suppress HBV replication. Nevert...

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Bibliographic Details
Main Authors: Mohammad Haque, Fengyang Lei, Xiaofang Xiong, Yijie Ren, Anil Kumar, Jugal Kishore Das, Xingcong Ren, Deyu Fang, Paul de Figueiredo, Jin-Ming Yang, Jianxun Song
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Immunology
Functional Aspects of Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305204

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http://www.sciencedirect.com/science/article/pii/S2589004220305204

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