MHC class II molecules enhance Toll-like receptor mediated innate immune responses.

BACKGROUND: Major histocompatibility complex (MHC) class II molecules play crucial roles in immune activation by presenting foreign peptides to antigen-specific T helper cells and thereby inducing adaptive immune responses. Although adaptive immunity is a highly effective defense system, it takes se...

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Bibliographic Details
Main Authors: Remo Frei, Johanna Steinle, Thomas Birchler, Susanne Loeliger, Caroline Roduit, Dirk Steinhoff, Reinhart Seibl, Katja Büchner, Reinhard Seger, Walter Reith, Roger P Lauener
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2808354?pdf=render